It is recommended that primary care clinicians a should assess patients for distress, depression, and or anxiety LOE I; b should conduct a more probing assessment for patients at a higher risk of depression eg, young patients, those with a history of prior psychiatric disease, and patients with low socioeconomic status; LOE III; and c should offer in office counseling and or pharmacotherapy and or refer to appropriate psycho oncology and mental health resources as clinically indicated if signs of distress, depression, or anxiety are present LOE I
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